Season 1

2017 · 26 episodes

Using a concoction of cartoons, comedy and live action, Dr. Yuck and his eccentric lab mates investigate the science behind the planet's ickiest things.

1Snot Now, Snot EverA new recruit changes the dynamics in the lab as Snot Faucet's cold threatens a sticky end for everyone!
2Pimple FeverWhen Septico's long lost brother comes to visit, he's repulsed by the grossness of the Yuck Lab - until he accidentally gets turned into a poop loving housefly.
3ArachnattackA horrible, hairy monster is unleashed as Septico's arch-nemesis arrives for an inspection of the Yuck Lab.
4Dirty Rotten Birthday GirlSeptico's attempt to throw Pristine a birthday party turns into a disgusting food eating competition.
5Fungus HumungusPristine's fear of fungus could destroy the lab.
6Enter the ToothwormSeptico tries his hand at wormcharming and Pristine hides a toothache when their dentist Aunt comes to visit.
7Septico's Felonious FunkSeptico's quest to take his body odor to new stinktacular heights forces Pristine to redesign her latest invention, the Smell-O-Vac, for her...
8That's So FlyWhen Septico's long lost brother comes to visit, he's repulsed by the grossness of the Yuck Lab - until he accidentally gets turned into a poop loving housefly.
9Gastrov FlatulinskySeptico challenges World Fart Champion Gastrov Flatulinsky to a farting competition.
10Attack of the Yucky PlantsWhen Septico's college crush, Botany "expert" Egregious Flytrap visits the lab, the gang tries to impress her with various disgusting plants, not realizing she wants to use those plants in a diabolical experiment.
11Urine LuckAfter Pristine turns down the chance to give a prestigious speech, Septico finds out she passed because she has urine control issues, and he's determined to whip her bladder in shape for her to give the speech.
12Parasite PiratesWhen a crew of pirate parasites takes over the Yuck Lab and infects the gang, Septico has to figure out a cure for the various parasites.
13No Guts, No GloryThe lab gang is left in charge of an annoying little girl with a tummy ache, as they scramble to prepare their submission for the World Yuckology Expo.
14The Yuck TrifectaWhen Pristine comes down with an increasingly more disgusting series of yucky conditions - Septico must save her from her body's own disgustingness.
15Pristine Hair-WolfA horrible, hairy monster is unleashed as Septico's arch-nemesis arrives for an inspection of the Yuck Lab.
16Kung PooSeptico's quest to do the perfect poop brings an ancient and dangerous curse on the lab.
17Antpocalypse Now!When the lab is overrun by an ant colony, Septico and the team have to bargain with the ants - before the O'Cleans can send in the Cleaners!
18Yuck Lab ZSeptico and Pristine seem to swap personalities after they're stung by zombie parasite wasps.
19Roach MotelSeptico's fascination with cockroaches causes chaos when he invites a specialist cockroach trainer to the lab.
20The Big StinkLeonidis' locks down the lab when his favorite stinky sandwich gets stolen, so Septico has to expose the gang to various stinky animals to find the culprit.
21Oh Rats!When it's revealed that Durp-E is secretly keeping a pet rat in the Yuck Lab, everyone is shocked as to whom the cringing, shrieking aversion to them is.
22Everything's All-Mite!Septico and the gang try to stop the O'Cleans from destroying the world's Mite population by creating an ad campaign to show that microscopic mites are actually cool.
23Around the S BendA monstrous Fatberg emerges from the sewers to wreak havoc on the lab!
24Blisters and Shingles and Warts! Oh My!All the gang get painful and gross skin conditions when Pristine attempts to cover her spying by helping Septico get into the record books for the world's biggest blister.
25All's Yuck That Ends Yuck Part 1Reeling from Pristine's betrayal, Septico advertises for her replacement and is visited by a seemingly perfect candidate.
26All's Yuck That Ends Yuck Part 2The fate of the lab is at stake as the gang is held hostage by their new boss.

Episodes